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Validated in WB, ICC/IF, IHC-P. Tested in Human, Mouse. Buy anti-LGR5 antibody, anti-Human, Mouse LGR5 Polyclonal Antibody- NP_001264155.1 (MBS856950) product datasheet at MyBioSource, Primary Antibodies Rabbit polyclonal LGR5 Antibody validated in IHC to detect human small intestine, colon, colon cancer, liver cancer tissues. Referenced in 3 publications. Clone STE-1-89-11.5 reacts with the human leucine-rich repeat-containing G- protein-coupled receptor (LGR) LGR5 but not with its close homologues LGR4 or LGR5 Antibody - Rabbit polyclonal antibody to human Leucine-rich repeat- containing G-protein coupled receptor 5. Validated for WB with human tissue.

Applications, WB, ELISA, FCM, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF( ICC). Rabbit LGR5 Rabbit pAb (A10545), validaed in WB,, IHC,, IF and tested in Human,, Mouse,, Rat. 100% Guaranteed. ABclonal provides free trial antibodies for 18 Apr 2012 LGR5 protein is specifically detected by anti-LGR5-antibody in human transfected MKN74 cells. The human gastric cancer cell lines MKN74, 30 May 2018 Saito-Diaz et al recently showed that inhibition of LRP6 (by siRNA and blocking antibodies) was still able to reverse β-catenin signalling in APC 14 Mar 2018 LGR5 immunohistochemical specificity in human colon and intestine. Two antibody clones for human LGR5 were used in this study: a rabbit Buy rabbit polyclonal antibody to LGR5 (A894). Validated Applications: WB and ICC. Reactivity: Human and Mouse.

Antibody-treated organoids were fixed, stained for. 18 Nov 2015 Targeting LGR5+ cells with an antibody-drug conjugate for the treatment of colon cancer. Melissa R. Junttila*,; Weiguang Mao,; Xi Wang,; Bu-Er 15 Jul 2020 Immunohistochemical staining was performed using anti-CD44, anti-LGR5, anti- ANXA2, and anti-DCLK1 antibodies.

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59 LGR5 Primary Antibodies: Thermo Fisher antibodies are validated for applications including western blotting, immunocytochemistry, flow cytometry, and chromatin immunoprecipitation. Secondary Antibodies Rabbit anti LGR5 antibody recognizes Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), also known as G-protein coupled receptor 49, G-protein coupled receptor 67 and G-protein coupled receptor HG38.

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Immunogen corresponding to recombinant … 59 LGR5 Primary Antibodies: Thermo Fisher antibodies are validated for applications including western blotting, immunocytochemistry, flow cytometry, and chromatin immunoprecipitation. LGR5 (Leucine-rich repeat G protein-coupled receptor 5) is thought of as a possible stem cell marker for the hair follicle and the epithelium of the intestine. LGR5 is only expressed in cycling crypt base columnar cells, which are thought to be genuine intestinal stem cells. LGR5-Targeted Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence Mol Cancer Ther. 2016 Jul;15(7):1580-90. doi: 10.1158/1535-7163.MCT-16-0114. Epub 2016 May 20.

This target gene encodes the protein 'leucine rich repeat containing G protein-coupled receptor 5' in humans and may also be known as FEX, GRP49, GPR49, GPR67, G-protein coupled receptor 49, and G-protein coupled receptor 67. Search results for lgr5 antibody at Sigma-Aldrich.
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Lgr5/GPR49 was detected in immersion fixed HEK293 human embryonic kidney cell line transfected with GFP (green) tagged mouse LGR5 using Mouse Anti-Human Lgr5/GPR49 Monoclonal Antibody (Catalog # MAB8078) at 10 µg/mL for 3 hours at room temperature. 2020-05-28 Antibody Type Monoclonal Host Species Mouse Immunogen Human LGR5 transfectant cells Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium … View specific protocols for Lgr5/GPR49 Antibody (NLS1236): Immunohistochemistry Protocol for GPR49/LGR5 Antibody (NLS1236) Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars. Immunohistochemistry-Paraffin Rabbit Polyclonal LGR5 antibody.
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LGR5 in breast cancer and ductal carcinoma in situ : a

(Showing 1 - 3 of 3 FAQs). This morning I have a customer who has purchased NBP1-28904 and would like to test it in flow cytometry. She is new to flow and is wondering if you might have a recommended protocol. This LGR5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 689-719 amino acids from human LGR5.

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innovative, full-length multispecific antibodies (Biclonics® and Triclonics™), antibody targeting EGFR and LGR5, in metastatic colorectal cancer (CRC).

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On the basis of these attributes, we generated two LGR5-targeting antibody-drug conjugates (ADC) by tethering the tubulin-inhibiting cytotoxic drug monomethyl auristatin E to a highly specific anti-LGR5 mAb via a protease cleavable or noncleavable chemical linker and compared them in receptor binding, cell internalization, and cytotoxic efficacy in cancer cells.

Antibody Type Monoclonal Host Species Mouse Immunogen Human LGR5 transfectant cells Formulation Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA). Preparation Specifications for LGR5 Antibody, anti-human. Overview. Clone STE-1-89-11.5 reacts with the human leucine-rich repeat-containing G-protein-coupled receptor (LGR) LGR5 but not with its close homologues LGR4 or LGR6. LGR5 Antibody (634J2E) is a mouse monoclonal IgG 1 provided at 100 µg/ml raised against a KLH-coupled peptide corresponding to amino acids 689-719 of LGR5 of human origin recommended for detection of LGR5 of human origin by WB and FCM Rabbit recombinant monoclonal LGR5 antibody [EPR3065Y]. Validated in WB and tested in Mouse, Rat, Human.